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Monoclonal Antibodies in Cancer Therapy: World Market Prospects 2010-2025
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| Features of this market research: |
This report gives you the following benefits in particular: 107 seiten | |||||||||||
| About this market survey: |
In 2009, monoclonal antibodies for cancer therapy generated total revenues of over $18bn worldwide. From 2010, that sector will benefit from new drugs and expanding indications for existing products. .....
In 2009, monoclonal antibodies for cancer therapy generated total revenues of over $18bn worldwide. From 2010, that sector will benefit from new drugs and expanding indications for existing products. Cancer incidence and prevalence are rising worldwide; studies reveal that incidence will rise by up to 40% by 2025. Worldwide, the treatment of cancer is a priority for healthcare providers, with high demand for efficacious and well-tolerated therapies. Where is the monoclonal antibody therapy market for cancer heading - technologically and commercially - from 2010 onwards? Our new report covers such questions, providing the information that you need. Our new report - Monoclonal Antibodies in Cancer Therapy: World Market Prospects 2010-2025 - explains how this market will develop, and where the opportunities will lie. We show how you can benefit from its developments and potential. There remain many unmet therapeutic needs in the treatment of cancer. There is also increasing demand for cancer monoclonal antibodies in developing countries. Novel monoclonal antibodies that demonstrate improved safety profiles – combined with high efficacies – can gain significant market shares from 2010 onwards. There remain high revenues to be made in this sector from 2010 to 2025, our new report explains. Monoclonal Antibodies in Cancer Therapy: World Market Prospects 2010-2025 covers the following monoclonal antibodies in detail: • Avastin • Mabthera/Rituxan • Herceptin • Erbitux • Vectibix • Campath. What sort of monoclonal antibodies are likely to enter the market from 2010 onwards? Where will the main opportunities lie, and what are the drivers and restraints in this market area? This report will provide you with the information that you need to understand current trends and future directions in the industry and market. Comprehensive analysis of the market for monoclonal antibodies in cancer therapy Monoclonal Antibodies in Cancer Therapy: World Market Prospects 2010-2025 examines this sector through a comprehensive review of information sources. We harness both primary and secondary research. This report provides unique sales forecasts, market share analyses, discussions of R&D pipelines and analyses of commercial drivers and restraints, including a SWOT analysis. There are over 45 tables and figures included, as well as two interviews with experts. The result is a comprehensive market- and industry-centred study, with detailed analyses and informed opinion to benefit your work. Report Highlights Companies Listed Abbott Abgenix Affimed American Cancer Society Amgen AstraZeneca Bayer Bayer Schering Pharma Biocon Biogen Idec BioTech Pharma Bristol-Myers Squibb Cell Therapeutics Center of Molecular Immunology [Havana, Cuba] Chugai Corixa (Acquired by GSK) Daiichi-Sankyo Dr. Reddy's Laboratories Elan Pharmaceuticals Eli Lilly Esteve European Medicines Agency (EMEA) Food and Drug Administration (FDA) [US] Fresenius Genentech Genmab Genzyme GlaxoSmithKline IDEC Pharmaceuticals ILEX Oncology ImClone Systems International Agency for Research on Cancer Johnson & Johnson Lance Armstrong Foundation mAbs Medarex Menarini Merck & Co. Merck KGaA Millennium Pharmaceuticals Morphotek National Health Service (NHS) [UK] National Institute for Health and Clinical Excellence (NICE) [UK] Novartis Oncoscience AG OSI Pharmaceuticals Pfizer Pierre Fabre Roche Southampton General Hospital [UK] Spectrum Pharmaceuticals State Food and Drug Administration (China State FDA) Takeda TeGenero TRION Pharma Tufts University UCB US Food and Drug Administration World Health Organisation (WHO) Wyeth YM Biosciences Zenyaku Kogyo [Fade out the market survey infos] |
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1. Executive Summary 1.1 Monoclonal Antibodies in Cancer Therapy: Market Review 1.2 Aims, Scope and Format of the Report 1.3 Research & Analysis Methods 2. Introduction to Monoclonal Antibodies for Cancer Therapy 2.1 Oncology is the Fifth-Largest Therapeutic Class Worldwide by Total Sales 2.2 The Oncology Market is Growing 2.3 Monoclonal Antibodies 2.3.1 What are Monoclonal Antibodies? 2.3.2 How do Monoclonal Antibody Therapies Work? 2.4 Categories of Monoclonal Antibodies for Therapeutic Use 2.4.1 Murine Antibodies 2.4.2 Chimeric and Humanised Antibodies 2.4.3 Fully Human Antibodies 2.4.4 Immunogenicity 2.5 Current Monoclonal Antibody Cancer Therapies 2.5.1 Avastin 2.5.2 MabThera/Rituxan 2.5.3 Herceptin 2.5.4 Erbitux 2.5.5 Vectibix 2.5.6 Campath 2.5.7 Mylotarg 2.5.8 Zevalin 2.5.9 Bexxar 2.5.10 Arzerra 2.5.11 TheraCIM 2.5.12 Removab 3. Cancer Therapy MAbs: World Market Prospects, 2010-2025 3.1 The Market for Monoclonal Antibodies in Cancer Therapy, 2009 3.2 The Biotech Market is Expanding Rapidly 3.2.1 Monoclonal Antibodies – Leading Class in the Pharma Biotech Market 3.2.2 Oncology is a Major Sales Driver in the Monoclonal Antibodies Market 3.3 Cancer Therapy MAbs: Market Forecast, 2010-2025 3.4 The Big Three Monoclonal Antibodies in Cancer Therapy 3.5 Generic Competition 3.6 Chimeric Antibodies 3.7 The Shift Towards Human Antibodies 4. The Leading Monoclonal Antibodies in Cancer Therapy, 2010-2025 4.1 The Leading Four Monoclonal Antibodies Accounted for 34% of the Global Cancer Drug Market in 2009 4.2 Avastin (Bevacizumab) 4.2.1 Avastin Leads the Market for Monoclonal Antibodies in Cancer Therapy 4.2.2 Avastin Will Show High Growth – But Will it Last? 4.3 MabThera/Rituxan (Rituximab) 4.3.1 MabThera/Rituxan Sales Forecast, 2010-2015 4.3.2 Long-Term Prospects for MabThera/Rituxan, 2015-2025 4.3.3 Competition for MabThera/Rituxan 4.3.4 Biosimilar MabThera/Rituxan 4.4 Herceptin (Trastuzumab) 4.4.1 Short Term Forecast for Herceptin 4.4.2 Long Term Prospects for Herceptin, 2015-2025 4.4.3 Herceptin's Major Competitors, 2010-2025 4.5 Erbitux (Cetuximab) 4.5.1 Erbitux Sales Forecast, 2010-2015 4.5.2 Erbitux Sales Forecast, 2015-2025 4.5.3 Erbitux’ Major Competitors, 2010-2025 4.6 Vectibix (Panitumumab) 4.6.1 Vectibix Sales Forecast, 2010-2025 4.7 Campath (Alemtuzumab) 4.7.1 Campath Sales Forecast, 2010-2025 4.8 Chapter Summary – The Leading Monoclonal Antibodies in Cancer Therapy, 2010-2025 5. SWOT Analysis 5.1 Key Market Drivers 5.1.1 The High Profile of Cancer 5.1.2 The Increasing Prevalence of Cancer 5.1.3 The High Economic Cost of Cancer 5.1.4 Drug Prices 5.1.5 Improvements in Accessibility 5.1.6 Incremental Improvements in Treatment in the Absence of a Complete Cure 5.1.7 New Production Methods Will Reduce Costs 5.1.8 Biologicals versus Chemically-Derived Pharmaceutical Products 5.1.9 Combining Existing Products 5.1.10 Monoclonal Antibodies Have a Lower Risk of Adverse Effects 5.1.11 Promising Pipelines 5.1.12 Personalised Medicine 5.2 Key Market Restraints 5.2.1 High Development Costs 5.2.2 Financial Limitations in Research and Development 5.2.3 Research Bias and 'Me-Too' Drugs 5.2.4 Risk Sharing 5.2.5 Public Health Initiatives 5.2.6 Competition is Fierce for Many Targets 5.2.7 Insufficient Efficacy as Monotherapies 5.2.8 Immunogenicity 5.2.9 Safety Concerns 5.2.10 Mode of Administration is a Limiting Factor 5.2.11 Biosimilar Monoclonal Antibodies 6. Cancer MAbs in the Leading National Pharmaceutical Markets, 2010-2025 6.1 Leading National Markets for Cancer Monoclonal Antibodies, 2009 6.2 National Market Forecasts, 2010-2025 6.3 US Cancer Monoclonal Antibodies Market: Prospects, 2010-2025 6.4 Japanese Cancer Monoclonal Antibodies Market: Prospects, 2010-2025 6.5 Cancer Monoclonal Antibody Markets in the Leading European Countries: Prospects, 2010-2025 6.6 Cancer Monoclonal Antibody Markets in China and India: Prospects, 2010-2025 7. R&D Pipeline for Monoclonal Antibody Cancer Therapies 7.1 New Technology – Monoclonal Antibody Fragments 7.1.1 Bispecific T-Cell Engagers 7.1.2 Tandabs 7.2 Conjugated versus Naked Antibodies 7.3 The Future of Fully Human MAbs 7.4 Competition for Prime Drug Targets 7.4.1 Tailored Medicine 7.5 Late-Stage Pipeline: Additional and Expanded Indications 7.5.1 Avastin 7.5.2 MabThera/Rituxan 7.5.3 Herceptin 7.5.4 Erbitux 7.6 Late-Stage R&D Pipeline Review 7.6.1 Dalotuzumab 7.6.2 Galiximab 7.6.3 Ipilimumab 7.6.4 Ramucirumab 7.6.5 Zalutumumab 8. Expert Opinions 8.1 Dr Mark Cragg 8.1.1 How Do Monoclonal Antibodies Treat Cancer? 8.1.2 The Future of Different Monoclonal Antibody Types 8.1.3 Threats and Limitations 8.1.4 Opportunities 8.1.5 Will Side Effects Limit Growth? 8.1.6 Future Developments 8.2 Dr Janice M. Reichert 8.2.1 Main Challenges 8.2.2 Main Opportunities 8.2.3 Side Effects 8.2.4 Future Developments and Pipelines 8.2.5 The Effect of Biosimilars 9. Conclusions 9.1 The Monoclonal Antibody Market, 2010-2025 9.2 Sales Growth for Monoclonal Antibody Cancer Therapies 9.3 The Monoclonal Antibody R&D Pipeline for Cancer Treatment 9.4 Expansion into Emerging Markets 9.5 Personalised Treatments 9.6 Future Prospects [Fade out table of contents] |
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Table 2.1 Monoclonal Antibody Technologies – Overview, 2010 Table 2.2 Targets and Indications for Selected FDA-Approved Antibodies, 2010 Table 3.1 Monoclonal Antibodies in Cancer Therapy: Overall Sales Forecast, 2010-2016 Table 3.2 Monoclonal Antibodies in Cancer Therapy: Overall Sales Forecast, 2017-2025 Table 3.3 Leading MAbs in Cancer Therapy: Sales & Market Shares, 2009, 2015, 2020 & 2025 Table 3.4 Cancer Monoclonal Antibodies: Sales & Market Shares by Class, 2009 Table 4.1 Avastin Sales Forecast, 2010-2016 Table 4.2 Avastin Sales Forecast, 2017-2025 Table 4.3 MabThera Sales Forecast, 2010-2016 Table 4.4 MabThera Sales Forecast, 2017-2025 Table 4.5 Herceptin Sales Forecast, 2010-2016 Table 4.6 Herceptin Sales Forecast, 2017-2025 Table 4.7 Erbitux Sales Forecast, 2010-2016 Table 4.8 Erbitux Sales Forecast, 2017-2025 Table 4.9 Vectibix Sales Forecast, 2010-2016 Table 4.10 Vectibix Sales Forecast, 2017-2025 Table 4.11 Campath Sales Forecast, 2010-2016 Table 4.12 Campath Sales Forecast, 2017-2025 Table 5.1 SWOT Chart for Cancer Monoclonal Antibodies, 2010-2025 Table 5.2 Side Effects of Monoclonal Antibody Therapy, 2010 Table 5.3 The Importance of Personalised Medicine in Oncology, 2010 Table 6.1 Leading National Markets for Cancer MAbs: Sales, 2009 Table 6.2 Leading National Markets for Cancer MAbs: Sales Forecasts, 2010-2016 Table 6.3 Leading National Markets for Cancer MAbs: Sales Forecasts, 2017-2025 Table 6.4 Leading National Markets for Cancer MAbs: Sales & Market Shares, 2009, 2015, 2020 & 2025 Table 7.1 Cancer MAb R&D Pipeline: Promising Agents in Phase III, 2010 Figure 3.1 Market Shares of the Monoclonal Antibody Therapeutic Areas, 2009 Figure 3.2 Sales of the Top Three Monoclonal Antibody Cancer Therapies, 2005-2009 Figure 3.3 Monoclonal Antibodies in Cancer Therapy: Overall Sales Forecast, 2010-2025 Figure 3.4 Leading MAbs in Cancer Therapy: Market Shares, 2009 Figure 3.5 Leading MAbs in Cancer Therapy: Market Shares, 2025 Figure 3.6 MAbs in Cancer Therapy: Market Shares by Class, 2009 Figure 4.1 Avastin Sales Forecast, 2010-2025 Figure 4.2 MabThera Sales Forecast, 2010-2025 Figure 4.3 Herceptin Sales Forecast, 2010-2025 Figure 4.4 Erbitux Sales Forecast, 2010-2025 Figure 4.5 Vectibix Sales Forecast, 2010-2025 Figure 4.6 Campath Sales Forecast, 2010-2025 Figure 4.7 Leading MAbs in Cancer Therapy: Sales, 2009, 2015 & 2025 Figure 4.8 Leading MAbs in Cancer Therapy: Sales Forecasts, 2010-2025 Figure 6.1 Leading National Market Shares, 2009 Figure 6.2 Leading National Market Shares, 2015 Figure 6.3 Leading National Market Shares, 2025 Figure 6.4 US: MAbs in Cancer Therapy Sales Forecast, 2010-2025 Figure 6.5 Japan: MAbs in Cancer Therapy Sales Forecast, 2010-2025 Figure 6.6 Leading European Countries: MAbs in Cancer Therapy Sales Forecasts, 2010-2025 Figure 6.7 China & India: MAbs in Cancer Therapy Sales Forecasts, 2010-2025 [Fade out list of tables / figures] |
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